Journal of Clinical Microbiology and Immunology

Volume 2, Issue 1 (2021)

Mini Review - Open Access
Importance of Autoimmune Mechanisms of Psoriasis and Role of Pathogenic

Richard H. Fu*

Pat Capps Covey College of Allied Health Professions, University of South Alabama, Alabama, 36688, USA

*Corresponding Author:
Richard H. Fu
Pat Capps Covey College of Allied Health Professions, University of South Alabama, Alabama, 36688, USA.
E-mail: richard@fu-qin.org

Received date: May 19, 2021; Accepted date: June 04, 2021; Published date: June 10, 2021

Citation: Fu RH. Importance of Autoimmune Mechanisms of Psoriasis and Role of Pathogenic. J Clin Microbiol Immunol. 2021;2(1): 9-13.

Copyright: © 2021 Fu RH. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Psoriasis could be a chronic, recurrent, immuno-inflammatory unwellness of the skin and joints related to important morbidity and mortality. skin disorder affects or so 2-4% of the Caucasian population worldwide. The precise immuno-inflammatory mechanisms resulting in skin disorder are still to be absolutely outlined. there’s rising proof supporting the existence of a relationship between changes in cuneal microbiota and development of skin disorder. underneath sure pathologic conditions related to dysbiosis of the skin microbiome, morbific microbes triggering aberrant immuno-inflammatory responses could spark the onset and relapses of skin disorder. sturdy association of sure human leucocyte antigens (HLAs) at the side of the morbific role of IL-17 suggests the involvement of reaction mechanisms in skin disorder. Multiple clinical trials targeting the IL-17/IL-23 axis in skin disorder are current. Here, we tend to review the rising findings suggesting the reaction nature of psoriasis skin disease of the skin condition and examine new therapeutic approaches for treatment of this chronic immuno-inflammatory disease.

Keywords

Autoimmune; Psoriasis; Pathogenic