Journal of Clinical Microbiology and Immunology

Volume 2, Issue 2 (2021)

Research Article - Open Access
Effect of Naturally Changes in Photoperiod and Temperature on Hematology and Cytokines in Striped Hamsters

Yan Wang1, Xiao-Kai Hu2, De-Li Xu2,*

1Hospital, Qufu Normal University, Qufu, 273165, Shandong Province, China

2College of Life Sciences, Qufu Normal University, Qufu, 273165, Shandong Province, China

*Corresponding Author:
De-Li Xu
College of Life Sciences, Qufu Normal University, 57 Jingxuan West Road, Qufu, 273165, People’s Republic of China.
Tel: +86-13280081296
E-mail: xudl1975@163.com; xudeli@mail.qfnu.edu.cn.

Received date: July 08, 2021; Accepted date: July 22, 2021; Published date: July 29, 2021

Citation: Wang Y, Hu XK, Xu DL. Effect of Naturally Changes in Photoperiod and Temperature on Hematology and Cytokines in Striped Hamsters. Arch Immuno Immunother. 2021;2(2):27-34.

Copyright: © 2021 Wang Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Previous research has shown that immune responses change seasonally in striped hamsters (Cricetulus barabensis) in the field. Many ecological factors change with the season. Hematological parameters and the levels of cytokines were investigated seasonally in this species under a semi-natural environment. Twenty-nine male and 30 female hamsters were randomly assigned into the winter, spring, summer, and autumn groups, respectively. All hematological parameters detected demonstrated seasonal variation, and mean corpuscular hemoglobin (MCH), mean corpuscular Hb concentration (MCHC), intermediate granulocytes percent (MID%) were higher, but red blood cell distribution width (RDW) was lower in males than in females, other hematological parameters did not differ between sexes. IL-2, IL-4, TNF-α, and INF-γ all changed seasonally and differed between sexes. IL-2 was the highest in the winter, whereas INF-γ was the highest in the spring, IL-4 was higher in the spring and autumn, and TNF-α was higher in the spring, and they were all affected by the interaction of season and sex. In summary, different parts of the immune system showed distinct patterns of seasonal variations, which are mainly triggered by naturally seasonal changes in photoperiod and temperature.

Keywords

Cytokine; Hematology; Striped hamsters (Cricetulus barabensis).



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