Volume 1, Issue 1 (2020)

1. Huntington G. On Chorea. Medical and Surgical Reporter: A Weekly Journal. 1872;26(15):317–2. 

2. Huntington G. On Chorea. J Neuropsychiatry Clin Neurosci. 2003;15(1):109–12. 

3. MacDonald, M. E., Gines, S., Gusella, J. F., and Wheeler, V. C. (2003) Huntington’s disease. Neuromolecular medicine 4, 7-20 2. 

4. Chen, S. M., Berthelier, V., Hamilton, J. B., O’Nuallain, B., and Wetzel, R. (2002) Amyloidlike features of polyglutamine aggregates and their assembly kinetics. Biochemistry 41, 7391- 7399 3. 

5. Lee, C. C., Walters, R. H., and Murphy, R. M. (2007) Reconsidering the mechanism of polyglutamine peptide aggregation. Biochemistry 46, 12810-12820 4. 

6. Thakur, A. K., Jayaraman, M., Mishra, R., Thakur, M., Chellgren, V. M., Byeon, I. J., Anjum, D. H., Kodali, R., Creamer, T. P., Conway, J. F., Gronenborn, A. M., and Wetzel, R. (2009) Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nature structural & molecular biology 16, 380-389 5. 

7. Aiken, C. T., Steffan, J. S., Guerrero, C. M., Khashwji, H., Lukacsovich, T., Simmons, D., Purcell, J. M., Menhaji, K., Zhu, Y. Z., Green, K., Laferla, F., Huang, L., Thompson, L. M., and Marsh, J. L. (2009) Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. The Journal of biological chemistry 284, 29427-29436 6. 

8. Thompson, L. M., Aiken, C. T., Kaltenbach, L. S., Agrawal, N., Illes, K., Khoshnan, A., Martinez-Vincente, M., Arrasate, M., O’Rourke, J. G., Khashwji, H., Lukacsovich, T., Zhu, Y. Z., Lau, A. L., Massey, A., Hayden, M. R., Zeitlin, S. O., Finkbeiner, S., Green, K. N., LaFerla, F. M., Bates, G., Huang, L., Patterson, P. H., Lo, D. C., Cuervo, A. M., Marsh, J. L., and Steffan, J. S. (2009) IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. The Journal of cell biology 187, 1083- 1099 7. 

9. Luo, S. Q., Vacher, C., Davies, J. E., and Rubinsztein, D. C. (2005) Cdk5 phosphorylation of huntingtin reduces itscleavage by caspases: implications for mutant huntingtin toxicity. Journal of Cell Biology 169, 647-656 8